307500-02-3

Basic information

• Product Name: 2-propenyl-(E,E)-N-methoxy-3-phenyl-2-propenimidate
• Synonyms: 2-propenyl-(E,E)-N-methoxy-3-phenyl-2-propenimidate
• CAS NO: 307500-02-3
• Molecular Weight: 217.268
• Mol File: 307500-02-3.mol

Chemical Properties

• CAS DataBase Reference: 2-propenyl-(E,E)-N-methoxy-3-phenyl-2-propenimidate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-propenyl-(E,E)-N-methoxy-3-phenyl-2-propenimidate(307500-02-3)
• EPA Substance Registry System: 2-propenyl-(E,E)-N-methoxy-3-phenyl-2-propenimidate(307500-02-3)

Safety Data

• Hazardous Substances Data: 307500-02-3(Hazardous Substances Data)

Upstream product

• 102-92-1 Cinnamoyl chloride 
• 112404-04-3 (E)-N-methoxy-3-phenyl-2-propenamide 
• 106-95-6 allyl bromide 

Relevant articles and documents

Radical Cyclization in Heterocycle Synthesis. 11. A Novel Synthesis of α,β-Disubstituted γ-Lactones via Sulfanyl Radical Addition-Cyclization Using Hydroximates as a Tether

A combination of sulfanyl radical addition-cyclization of dienes connected with hydroximates and subsequent conversion of the resulting cyclic hydroximate to the lactones provides a novel method for the construction of α,β-disubstituted γ-lactones. Upon treatment with thiophenol in the presence of AIBN, dienes connected with hydroximates smoothly underwent sulfanyl radical addition-cyclization to give cyclic cis- and trans-hydroximates. Hydrolysis of cyclic hydroximates gave the desired cis- and trans-lactones in high yield. This method was successfully applied to the practical synthesis of (±)-oxo-parabenzlactone.