307523-22-4Relevant academic research and scientific papers
Propanoic acid derivatives that inhibit the binding of integrins to their receptors
-
Page column 38, (2008/06/13)
A compound of the structure A method for the inhibition of the binding of α4β1integrin to its receptors, for example VCAM-1(vascular cell adhesion molecule-1) and fibronectin; pharmaceutically active compositions comprising these compounds; and the use of these compounds for the control or prevention of diseases states in which α4β1is involved are also disclosed.
Propanoic acid derivatives that inhibit the binding of integrins to their receptors
-
Page 27, (2008/06/13)
A method for the inhibition of the binding of α4β1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds (I) that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which α4β1 is involved. All substituents are as defined in the application.
