307538-36-9Relevant articles and documents
Potent inhibitors of Huntingtin protein aggregation in a cell-based assay
Rinderspacher, Alison,Cremona, Maria Laura,Liu, Yidong,Deng, Shi-Xian,Xie, Yuli,Gong, Gangli,Aulner, Nathalie,Toebben, Udo,Myers, Katherine,Chung, Caty,Andersen, Monique,Vidovic, Dusica,Schuerer, Stephan,Branden, Lars,Yamamoto, Ai,Landry, Donald W.
experimental part, p. 1715 - 1717 (2009/12/03)
A quinazoline that decreases polyglutamine aggregate burden in a cell-based assay was identified from a high-throughput screen of a chemical-compound library, provided by the NIH Molecular Libraries Small Molecule Repository (MLSMR). A structure and activ