307543-29-9Relevant academic research and scientific papers
Synthesis, and antimycobacterial and cytotoxic evaluation of certain fluoroquinolone derivatives
Sheu, Jia-Yuh,Chen, Yeh-Long,Tzeng, Cherng-Chyi,Hsu, Shu-Lin,Fang, Kuo-Chang,Wang, Tai-Chi
, p. 2481 - 2489 (2007/10/03)
Certain 1-ethyl- and 1-aryl-6-fluoro-1,4-dihydroquinol-4-one derivatives were synthesized and evaluated for antimycobacterial and cytotoxic activities. Preliminary results indicated that, for 1-aryl-6-fluoroquinolones, both 7-(piperazin-1-yl)- and 7-(4-me
6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions
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, (2008/06/13)
The present invention discloses a novel 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives (formula I), with a process for their preparation, and with pharmaceutical compositions containing them as
Synthesis and antibacterial evaluation of certain quinolone derivatives
Chen,Fang,Sheu,Hsu,Tzeng
, p. 2374 - 2377 (2007/10/03)
A number of 7-substituted quinolone derivatives were synthesized and evaluated for antibacterial and cytotoxic activities. Preliminary results indicated that most compounds tested in this study demonstrated better activity against methicillin-resistant St
Synthesis, antibacterial, and cytotoxic evaluation of certain 7-substituted norfloxacin derivatives
Fang,Chen,Sheu,Wang,Tzeng
, p. 3809 - 3812 (2007/10/03)
We report herein the synthesis and biological evaluation of two series of 7-substituted norfloxacin derivatives. Most compounds tested in this study demonstrated better activity against methicillin-resistant Staphylococcus aureus than norfloxacin. Prelimi
