30779-96-5Relevant articles and documents
Mitsunobu coupling of 7-hydroxycoumarins with allylic and propargylic alcohols: A facile direct access to tertiary allyl coumarinyl ethers
Ganguly, Nemai C.,Sukai, Arun K.,Dutta, Sanjoy,De, Prithwiraj
, p. 380 - 382 (2007/10/03)
Allylic and propargylic alcohols are coupled with 7-hydroxycoumarins under Mitsunobu conditions using diethyl azodicarboxylate (DEAD) and triphenylphosphine to afford the corresponding coumarinyl ethers without any rearrangement in good-to-acceptable yields. This route provides direct access to the 1,1-dimethylallyloxycoumarins which are key intermediates for the Claisen rearrangement-based synthesis of linear and angular coumarins.