3081-67-2

Basic information

• Product Name: 1-(2,3-Dimethoxyphenyl)acetone
• Synonyms: 1-(2,3-Dimethoxyphenyl)-2-propanone;1-(2,3-Dimethoxyphenyl)acetone
• CAS NO: 3081-67-2
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.2271
• Mol File: 3081-67-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 270.6°Cat760mmHg
• Flash Point: 108.1°C
• Appearance: /
• Density: 1.056g/cm³
• Vapor Pressure: 0.00678mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: 1-(2,3-Dimethoxyphenyl)acetone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3-Dimethoxyphenyl)acetone(3081-67-2)
• EPA Substance Registry System: 1-(2,3-Dimethoxyphenyl)acetone(3081-67-2)

Safety Data

• Hazardous Substances Data: 3081-67-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14O3/c1-8(12)7-9-5-4-6-10(13-2)11(9)14-3/h4-6H,7H2,1-3H3

Upstream product

• 33414-37-8 1-(2',3'-dimethoxyphenyl)propan-2-ol 
• 91-16-7 1,2-dimethoxybenzene 

Downstream Products

• 26158-25-8 N'-[2-(2,3-Dimethoxy-phenyl)-1-methyl-eth-(E)-ylidene]-hydrazinecarbodithioic acid methyl ester 
• 33414-37-8 1-(2',3'-dimethoxyphenyl)propan-2-ol 
• 195001-42-4 3-(2',3'-dimethoxyphenyl)butan-2-one 
• 170753-24-9 4-(2',3'-dimethoxyphenyl)-4-methyl-3-vinylcyclohex-2-enone 
• 195001-61-7 6-(2',3'-dimethoxyphenyl)-3-methoxy-6-methylcyclohex-2-enone 

Relevant articles and documents

Development of a robust and practical process for the Darzens condensation and α,β-epoxide rearrangement: Scope and limitations of the methodology

A practical and robust process for the Darzens condensation of substituted benzaldehydes and subsequent α,β-epoxy rearrangement is reported. The process developed is both amenable to large scale and parallel synthesis. While electron-poor benzaldehydes gave mixtures of aryl ketones and 2-substituted aryl ketones in mediocre to low yields, electron-rich benzaldehydes were found to react in high yields with complete regioselectivity to form 2-substituted aryl ketones. Georg Thieme Verlag Stuttgart.