30811-19-9 Usage
Uses
Used in Research and Development:
L-4-HYDROXYPHENYL-3,5-D2-ALANINE is used as a research compound for studying the synthesis, metabolism, and functions of neurotransmitters, particularly dopamine and its related compounds. The isotopically labeled version of the compound enables researchers to monitor its behavior in biological systems, providing valuable insights into the underlying mechanisms of neurotransmission and related neurological processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, L-4-HYDROXYPHENYL-3,5-D2-ALANINE is used as a key intermediate in the synthesis of various drugs targeting neurological and psychiatric disorders. Its isotopically labeled nature allows for the development of novel therapeutic agents with improved pharmacokinetic properties, potentially leading to more effective treatments for conditions such as Parkinson's disease, schizophrenia, and depression.
Used in Diagnostic Applications:
L-4-HYDROXYPHENYL-3,5-D2-ALANINE can be employed as a diagnostic tool in the detection and monitoring of neurotransmitter-related disorders. The isotopically labeled compound can be used to track the levels of neurotransmitters in patients, aiding in the diagnosis and treatment of conditions such as attention deficit hyperactivity disorder (ADHD) and other dopamine-related disorders.
Used in Neurochemistry and Neurophysiology:
In the fields of neurochemistry and neurophysiology, L-4-HYDROXYPHENYL-3,5-D2-ALANINE serves as an essential research tool for understanding the role of dopamine and its precursors in the central nervous system. L-4-HYDROXYPHENYL-3,5-D2-ALANINE can be used to study the regulation of dopamine synthesis, release, and reuptake, as well as its involvement in various neurological processes, including reward, motivation, and motor control.
Check Digit Verification of cas no
The CAS Registry Mumber 30811-19-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,8,1 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 30811-19:
(7*3)+(6*0)+(5*8)+(4*1)+(3*1)+(2*1)+(1*9)=79
79 % 10 = 9
So 30811-19-9 is a valid CAS Registry Number.
30811-19-9Relevant academic research and scientific papers
Forneris, Clarissa C.,Ozturk, Seyma,Sorensen, Erik J.,Seyedsayamdost, Mohammad R.
, p. 3231 - 3237 (2018)
The biosynthesis of glycopeptide antibiotics (GPAs) has been an active area of research for decades. But, insights into the activity of the cytochrome P450 enzymes required for installing the aromatic crosslinks, which form their cup-shaped topologies and
Synthesis of deuterium, tritium and 14-carbon labelled isotopomers of L-DOPA
Kozlowska,Kanska
, p. 1763 - 1769 (2008/09/17)
The synthesis of five isotopomers of L-DOPA labelled selectively with deuterium, tritium and 14C is reported. The isotopomers of L-tyrosine, the intermediate substrates for this synthesis, were obtained using chemical and enzymatic methods. Sel
Synthesis of phenylalanines regiospecifically labelled with deuterium in the aromatic ring
Nishiyama,Oba,Ueno,Morita,Nakamura,Kainosho
, p. 831 - 837 (2007/10/02)
Phenylalanines regiospecifically labelled with deuterium in the aromatic ring can be prepared through the hydrogenolysis of tyrosine tetrazolyl ethers using D2 gas and a medium pressure catalytic hydrogenator.
PROPERTIES OF AROMATIC RESIDUES IN FERRICYTOCHROME c3 OF DESULFOVIBRIO VULGARIS MIYAZAKI F STUDIED BY 1H NMR
Park, Jang-Su,Enoki, Minoru,Ohbu, Ayako,Fan, Kejung,Niki, Katsumi,et al.
, p. 343 - 353 (2007/10/02)
Conditions for the specific labelling of the tetrahaeme protein cytochrome c3 of Desulfovibrio vulgaris Miyazaki F during culture of this sulphate-reducing bacterium in a medium were established.Phenylalanine and tyrosine residues were specific
