308123-66-2Relevant academic research and scientific papers
Studies on phosphoroheterocycle chemistry I: A facile synthesis of new tricyclic phosphoroheterocycles 1,3,2-oxazaphospholidino(or oxazaphosphorino)[3,2-a][1,3,2]benzodiazaphosphorines
Deng,Liu,Huang,Chen
, p. 1631 - 1634 (2007/10/03)
Reaction procedures have been developed for the preparation of structurally different phosphoroheterocyclic compounds. Firstly, the treatment of PCl3 with functionalized compound N-ethyl-2-(β-hydroxyethyl)aminobenzamide gave chlorinated phosphoroheterocycle, 1-(2-chloroethyl)-3-ethyl-2,3-dihydro-1,3,2-benzodiazaphosphorin-4(1H)-one 2-oxide. Secondly, novel tricyclic phosphoroheterocycles, 1,3,2-oxazaphospholidino(or oxazaphosphorino)[3,2-a][1,3,2]benzodiazaphosphorines, have been conveniently synthesized by cyclization of tris(diethylamino)phosphine with 2-(N-(β or γ-hydroxyalkyl)aminobenzamides. Finally, the reaction of 2-(N-ethoxycarbonylmethyl)amino-N-(2′-hydroxyethyl)benzamide with P(NEt2)3 afforded five-membered phosphoroheterocycle, 3-(2′-N-ethoxycarbonylmethylamino)benzoyl-2-diethylamino-1,3,2- oxazaphospholidine-2-sulfide. Additionally, the preliminary bioassays showed that several title compounds possessed herbicidal activity to some extent.
