308144-40-3Relevant academic research and scientific papers
Macrocyclic Hydrocarbons with Rigid and Flexible Building Blocks
Windisch,Voì?gtle,Nieger,Lahtinen,Rissanen
, p. 642 - 653 (2007/10/03)
We report the synthesis of a series of new hydrocarbon macrocycles. Following the dithia-phane route, four large rings 3-6 of the cyclophane type containing different numbers of ring atoms were prepared confirming the general applicability of this route compared to alternative macrocyclizations. Cycle 3 is the hydrocarbon analogue to the tetralactam and the sulfone amide macrocycles 1 and 2 used in many rotaxane syntheses. The macrocycles synthesized here are supposed to be uselful as wheels in the slipping approach to rotaxanes to further establish a reference system for the cavity size of cyclic compounds by comparing them to certain complemenatry blocking groups. The x-ray data obtained of the macrocycles 3, 5, and 6 reveal the cavity shape and size in solid state.
