308272-30-2Relevant academic research and scientific papers
1,3-BENZOTHIAZINONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF
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Page/Page column 22, (2010/02/13)
As prophylactic and/or therapeutic agents for cardiovascular diseases, bone or joint diseases, infectious diseases, inflammatory diseases, kidney diseases, etc. having safe and excellent effects of cell death inhibition, MIF binding, etc., there are provi
Design and synthesis of glycolic and mandelic acid derivatives as factor Xa inhibitors
Su, Ting,Wu, Yanhong,Doughan, Brandon,Kane-Maguire, Kim,Marlowe, Charles K,Kanter, James P,Woolfrey, John,Huang, Brian,Wong, Paul,Sinha, Uma,Park, Gary,Malinowski, John,Hollenbach, Stan,Scarborough, Robert M,Zhu, Bing-Yan
, p. 2279 - 2282 (2007/10/03)
A series of glycolic and mandelic acid derivatives was synthesized and investigated for their factor Xa inhibitory activity. These analogues are highly potent and selective inhibitors against fXa. In a rabbit deep vein thrombosis model, compound 26 showed
