308276-64-4

Upstream product

• 64-04-0 phenethylamine 
• 308276-66-6 tert-butyl 2-(5-bromo-2-(methylthio)-6-oxopyrimidin-1(6H)-yl)acetate 
• 308276-63-3 tert-butyl 2-(6-oxo-5-(phenethylamino)-2-phenylpyrimidin-1(6H)-yl)acetate 

Downstream Products

• 308276-65-5 C₃₆H₃₄N₆O₄ 

Relevant academic research and scientific papers

MASP-2 INHIBITORS AND METHODS OF USE

The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.

Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade

The invention relates to substituted polycyclic aryl and heteroaryl pyrimidinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.