30835-65-5

Usage

Class

Cyclopenta(a)phenanthrenes

Derivative

Steroids

Structural Relation

Hormones like testosterone and estrogen

Industry

Pharmaceutical

Therapeutic Applications

Anti-inflammatory and anti-cancer properties

Enzyme Inhibition

17-beta-hydroxysteroid dehydrogenase

Role in Metabolism

Plays a role in the metabolism of steroids in the body

Usage

Chemical intermediate in organic synthesis

Production

Various pharmaceuticals and other organic compounds

InChI:InChI=1/C18H14O/c1-11-10-12-4-2-3-5-13(12)15-7-6-14-16(18(11)15)8-9-17(14)19/h2-7,10H,8-9H2,1H3

Upstream product

• 30835-64-4 Phosphoric acid diethyl ester 7-methyl-17-oxo-16,17-dihydro-15H-cyclopenta[a]phenanthren-11-yl ester 
• 30856-55-4 Acetic acid 7-methyl-17-oxo-16,17-dihydro-15H-cyclopenta[a]phenanthren-11-yl ester 
• 30835-60-0 11-Hydroxy-7-methyl-15,16-dihydro-cyclopenta[a]phenanthren-17-one 

Relevant academic research and scientific papers

A Kinetic Investigation of the Hydroxide-catalysed Detritiation of Various -15,16-Dihydrocyclopentaphenanthren-17-ones and Related Compounds

The hydroxide-catalysed detritiation rate constants from the C-16 position of a series of substituted -15,16-dihydrocyclopentaphenanthren-17-ones have been measured in a 90:10 (v/v) water-dioxane mixture at 25 deg C.The results show that methyl group substitution brings with it, in addition to the costumary deactivating effect, a marked acceleration in rate, which probably has its origin in steric strain considerations.Similar studies involving the analogous position in a number of related ketones (benzindanone, indanone, and cyclopentanone) show that the rates are not simply a function of the number of additional benzene rings but depend on their position relative to the cyclopentanone system.