308359-16-2

Basic information

• Product Name: C₃₆H₄₀N₆O₆S
• Synonyms: C₃₆H₄₀N₆O₆S
• CAS NO: 308359-16-2
• Molecular Weight: 684.816
• Mol File: 308359-16-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₀N₆O₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₀N₆O₆S(308359-16-2)
• EPA Substance Registry System: C₃₆H₄₀N₆O₆S(308359-16-2)

Safety Data

• Hazardous Substances Data: 308359-16-2(Hazardous Substances Data)

Upstream product

• 82029-27-4 safracin B 
• 103-72-0 phenyl isothiocyanate 
• 773837-37-9 sodium cyanide 
• 96996-50-8 cyanosafracin B 

Relevant articles and documents

Preparation method and intermediate of trabectedin

The invention provides a novel preparation method for trabectedin. According to the method, safracin B is used as a starting raw material and undergoes a series of reactions to synthesize trabectedin. The raw material used in the method is easily available; the method is few in synthesis steps; a highly toxic organotin reagent is not used in the method, so the method is safe and low in cost; and the method has good industrial application value.

Synthesis of ecteinascidin 743 analogues from cyanosafracin B: Isolation of a kinetically stable quinoneimine tautomer of a 5-hydroxyindole

Phthalimido derivatives of cyanosafracin B have been synthesized as analogues of the antitumor agent ecteinascidin 743. As part of this study, a quinoneimine has been prepared, which is a kinetically stable tautomer of a 5-hydroxyindole. This quinoneimine tautomer is stable under acidic and mild basic conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.