30838-11-0

Upstream product

• 4755-77-5 Ethyl oxalyl chloride 
• 4424-17-3 2-aminobenzanilide 
• 95-92-1 oxalic acid diethyl ester 
• 62-53-3 aniline 
• 118-48-9 isatoic anhydride 

Downstream Products

• 31199-65-2 N-(2-Dimethylamino-ethyl)-N'-(2-phenylcarbamoyl-phenyl)-oxalamide 
• 30838-16-5 ethyl 4-oxo-3-phenyl-3,4-dihydroquinazoline-2-carboxylate 
• 36137-05-0 2-(2-Hydroxy-2,2-diphenyl-acetylamino)-N-phenyl-benzamide 
• 1263153-07-6 2-[hydroxy(diphenyl)methyl]-4-oxo-3-phenyl-3,4-dihydroquinazoline 
• 36137-09-4 2-oxo-N,3,3-triphenylindoline-7-carboxamide 

Relevant academic research and scientific papers

Synthesis of 3-aryl-2-[hydroxy(diaryl)methyl]-4-oxo-3,4-dihydroquinazolines

By heating arylamides of N-ethoxalylanthranilic acid in the acetic acid mediun in the presence of triethylamine the corresponding ethyl 3-aryl-4-oxo-3,4-dihydroquinazoline-2-carboxylates were obtained. The latter in the conditions of the Grignard reaction formed 3-aryl-2-[hydroxy-(diaryl)methyl] -4-oxo-3,4-dihydroquinazolines. Pleiades Publishing, Ltd., 2010.

Synthetic studies on 3-arylquinazolin-4-ones: Intramolecular nucleophilic aromatic substitution reaction of 2-carboxamido-3-arylquinazolin-4-ones and its application to the synthesis of secondary aryl amines

The general synthesis and a novel intramolecular nucleophilic aromatic substitution (SNAr) reaction of 2-carboxamido-3-arylquinazolin-4- ones, a potentially useful scaffold in the field of medicinal chemistry, are described. The synthetic utili