30857-55-7

Upstream product

• 15332-37-3 1-(hex-1-yn-1-yl)-cyclohex-1-ene 
• 15332-33-9 1-(hex-1-ynyl)cyclohexanol 
• 28075-50-5 cyclohex-1-en-1-yl trifluoromethane sulfonate 
• 108-94-1 cyclohexanone 
• 4233-18-5 bicyclohexylidene 
• 84114-87-4 1-(Cyclohex-1-enyl)cyclohex-1-yl Hydroperoxide 
• 32359-01-6 hexenylmagnesium bromide 

Downstream Products

• 1188906-02-6 1-(1,2-dichlorocyclohexyl)hexan-1-one 
• 126208-34-2 1-((1S,2R)-1,2-Dichloro-cyclohexyl)-hexan-1-one 

Relevant academic research and scientific papers

Regioselective radical cyclization initiated by the reaction of allylic hydroperoxides with iron(II) sulfate

Treatment of 1-methyl-2-methylene-1-cyclohexyl hydroperoxide with a mixture of FeSO4/CuCl2 yielded 1-(1-chlorocyclohexyl)ethanone as the major product consistent with 6-endo-trig cyclization of the intermediate 5-acetylhex-5-enyl rad

Bronsted acid-catalyzed hydration of alkynes: A convenient route to diverse carbonyl compounds

Trifluoromethanesulfonic acid or trifluoromethanesulfonimide efficiently catalyzes the hydration of alkynes without a metal catalyst to afford a wide variety of carbonyl compounds in good to excellent yields with perfect regioselectivities.

Dehydration-hydration of α-alkynols over zeolite catalyst. Selective synthesis of conjugated enynes and α,β-unsaturated ketones

α-Alkynols 1 are convened in high yield and selectivity into conjugated enynes 2 or α,β-unsaturated ketones 3 by treatment with acid zeolites. The exclusive production of compounds 2 or 3 depends on the nature of the starting material 1 and experimental conditions.

Palladium(0)-catalysed Cross-coupling Reactions of α-Alkoxyalkenylstannanes and α-Alkoxyalkenylzincs

α-Alkoxyalkenylstannanes prepared by the Pd0-catalysed hydrostannylation of 1-alkoxyalk-1-ynes, undergo Pd0-catalysed Stille-type cross-coupling reactions with acid chlorides, aryl iodides and alkenyl trifluoromethanesulfonates.In the most complex case, an enol ether moiety was appended to a carbapenem nucleus.The coupling reaction was strongly dependent upon solvent, temperature, and added ligands.The method substantially extends the use of metallated enol ethers as nucleophilic acylation agents.