308830-29-7Relevant articles and documents
MMP-13 selective isonipecotamide α-sulfone hydroxamates
Kolodziej, Stephen A.,Hockerman, Susan L.,Decrescenzo, Gary A.,McDonald, Joseph J.,Mischke, Debbie A.,Munie, Grace E.,Fletcher, Theresa R.,Stehle, Nathan,Swearingen, Craig,Becker, Daniel P.
scheme or table, p. 3561 - 3564 (2010/10/01)
A series of N-aryl isonipecotamide α-sulfone hydroxamate derivatives has been prepared utilizing a combination of solution-phase and resin-bound library technologies to afford compounds that are potent and highly selective for MMP-13.