30923-64-9

Basic information

• Product Name: 1,3-dicyclopropylpropane-1,3-dione
• Synonyms: 1,3-dicyclopropylpropane-1,3-dione
• CAS NO: 30923-64-9
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.19038
• Mol File: 30923-64-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 252.7±13.0 °C(Predicted)
• Appearance: /
• Density: 1.227±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 10.30±0.20(Predicted)
• CAS DataBase Reference: 1,3-dicyclopropylpropane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dicyclopropylpropane-1,3-dione(30923-64-9)
• EPA Substance Registry System: 1,3-dicyclopropylpropane-1,3-dione(30923-64-9)

Safety Data

• Hazardous Substances Data: 30923-64-9(Hazardous Substances Data)

Usage

General Description

1,3-dicyclopropylpropane-1,3-dione is a chemical compound with a molecular formula of C9H12O2. It is a cyclic ketone with two cyclopropyl moieties and a carbonyl group, and is commonly referred to as diketocyclopropane. It has a unique three-membered ring structure, making it a highly strained molecule with interesting reactivity and potential applications in organic synthesis. It is used as a reagent in the preparation of various organic compounds and has been studied for its potential use in materials science and medicinal chemistry. Its unusual structure and reactivity make 1,3-dicyclopropylpropane-1,3-dione an intriguing compound for researchers in the field of organic chemistry.

Upstream product

• 765-43-5 Cyclopropyl methyl ketone 
• 2868-37-3 methyl cyclopropylcarboxylate 
• 4606-07-9 ethyl cyclopropylcarboxylate 

Downstream Products

• 1288339-30-9 3,5-dicyclopropyl-1H-pyrazole 
• 1288339-42-3 2-chloro-N-[4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)phenyl]acetamide 
• 1288340-53-3 4-(4-chloro-3,5-dicyclopropyl-1H-pyrazol-1-yl)-3-fluoroaniline 
• 1288339-38-7 4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)-3-fluoroaniline 
• 1288339-37-6 4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)aniline 
• 1288340-51-1 4-chloro-3,5-dicyclopropyl-1-(2-fluoro-4-nitrophenyl)-1H-pyrazole 
• 1288339-32-1 3,5-dicyclopropyl-1-(2-fluoro-4-nitrophenyl)-1H-pyrazole 
• 1288339-31-0 3,5-dicyclopropyl-1-(4-nitrophenyl)-1H-pyrazole 
• 1288341-01-4 N-[4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)phenyl]-2-morpholinoacetamide 
• 1288341-00-3 tert-butyl 4-(2-(4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)phenylamino)-2-oxoethyl)piperazine-1-carboxylate 
• 1288340-99-7 N-[4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)phenyl]-2-(piperazin-1-yl)acetamide hydrochloride 
• 1288342-41-5 N-[4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)phenyl]-2-(piperazin-1-yl)acetamide 
• 1288340-73-7 N-[4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)phenyl]-5-methylisoxazole-4-carboxamide 
• 1288340-70-4 N-[4-(3,5-dicyclopropyl-1H-pyrazol-1-yl)phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide 

Relevant articles and documents

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NEW CRTH2 ANTAGONISTS

The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.

Compounds Useful In Therapy

Compounds of Formula (I): and pharmaceutically acceptable salts, solvates (including hydrates) of said compounds and salts, or prodrugs of said compound, or pharmaceutically acceptable salts or solvates of said prodrugs, wherein the substituents are as herein defined, are useful in therapy, for example they may be useful for treating progesterone-mediated conditions such as endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), or chronic pelvic pain syndrome.