309248-20-2Relevant academic research and scientific papers
Preparation of 5-unsubstituted 4-formylpyrrole-2-carboxylates and conversion to cycloalkano-oligopyrroles
Fumoto, Yumiko,Uno, Hidemitsu,Ito, Satoshi,Tsugumi, Yuka,Sasaki, Maki,Kitawaki, Yukiko,Ono, Noboru
, p. 2977 - 2981 (2007/10/03)
Ethyl 4-formylpyrrole-2-carboxylates were prepared from nitroacetaldehyde dimethyl acetal in 9-50% yields using the Barton-Zard reaction. These formylpyrroles were successfully transformed to cycloalkano-oligopyrroles. The conformation of cyclononatripyrroles in CDCl3 was found to be a crown form based on the NMR analysis, while cyclododecatetrapyrroles were in two interconverting boat and chair conformations.
