309264-66-2Relevant academic research and scientific papers
Dehydrative cyclization of serine, threonine, and cysteine residues catalyzed by molybdenum(VI) oxo compounds
Sakakura, Akira,Kondo, Rei,Umemura, Shuhei,Ishihara, Kazuaki
body text, p. 2102 - 2109 (2009/07/11)
Commercially available molybdenum(VI) oxides such as (NH4)2MoO4, (NH4)6Mo7O24·4H2O, MoO2(acac)2, and MoO2(TMHD)2 are highly
Molybdenum oxides as highly effective dehydrative cyclization catalysts for the synthesis of oxazolines and thiazolines
Sakakura, Akira,Kondo, Rei,Ishihara, Kazuaki
, p. 1971 - 1974 (2007/10/03)
(Chemical Equation Presented) In the presence of molybdenum oxide the dehydrative cyclization of N-acylserines, N-acylthreonines, and N-acylcysteines can be carried out under Dean-Stark conditions in toluene to give oxazolines and thiazolines. The ammoniu
A biomimetic synthesis of thiazolines using hexaphenyloxodiphosphonium trifluoromethanesulfonate
You, Shu-Li,Razavi, Hossein,Kelly, Jeffery W.
, p. 83 - 85 (2007/10/03)
Most chemical syntheses of thiazolines use serine residues, whereas nature employs cysteine residues. In a biomimetic approach, [(Ph3P+)2O](OTf-)2 was used to promote triphenylmethyl (Tr) deprotection
Titanium(IV)-mediated tandem deprotection-cyclodehydration of protected cysteine N-amides: Biomimetic syntheses of thiazoline- and thiazole-containing heterocycles
Raman, Prakash,Razavi, Hossein,Kelly, Jeffery W.
, p. 3289 - 3292 (2007/10/03)
(matrix presented) The scope and limitations of TiCl4-mediated Δ2-thiazoline synthesis via tandem deprotection-dehydrocyclization of trityl-protected cysteine N-amides is presented. While chemical yields are acceptable (53-96%), the
