309273-07-2Relevant academic research and scientific papers
Mild, efficient Fischer indole synthesis using 2,4,6-trichloro-1,3,5- triazine (TCT)
Siddalingamurthy, Eranna,Mahadevan, Kittappa M.,Masagalli, Jagadeesh N.,Harishkumar, Hosanagara N.
supporting information, p. 5591 - 5596 (2013/09/23)
Mild and efficient protocol for the Fischer indole synthesis using TCT has been described. TCT serves as a mild and inexpensive catalyst. Under these conditions several functional groups such as ester, cyano, sulfone, amides, and ethers are tolerated. By this method, many functionalized analytically pure indoles were prepared easily without the need of purification.
Rh2(II)-catalyzed selective aminomethylene migration from styryl azides
Kong, Chen,Jana, Navendu,Driver, Tom G.
, p. 824 - 827 (2013/03/29)
Rh2(II)-Carboxylate complexes were discovered to promote the selective migration of aminomethylenes in β,β-disubstituted styryl azides to form 2,3-disubstituted indoles. Mechanistic data are also presented that suggest that the migration occurs stepwise before diffusion of the iminium ion.
