309290-76-4Relevant academic research and scientific papers
Tandem addition/cyclization for synthesis of 2-aroyl benzofurans and 2-aroyl indoles by carbopalladation of nitriles
Gong, Julin,Hu, Kun,Shao, Yinlin,Li, Renhao,Zhang, Yetong,Hu, Maolin,Chen, Jiuxi
, p. 488 - 494 (2020/02/03)
The first example of the palladium-catalyzed tandem addition/cyclization of 2-(2-acylphenoxy)acetonitriles with arylboronic acids has been developed, providing a new strategy for the synthesis of 2-aroyl benzofurans with excellent chemoselectivity and wid
A new synthetic route of 2-aroyl- and 2-benzyl-benzofurans and their application in the total synthesis of a metabolite isolated from dorstenia gigas
Correa, Christian,Cruz, Maria Del Carmen,Jimnez, Fabiola,Zepeda, L. Gerardo,Tamariz, Joaqun
experimental part, p. 991 - 999 (2009/04/06)
The Lewis acid-catalyzed cyclization of the (Z)-3-(dimethylamino)-2- aryloxy-1-arylprop-2-en-1-ones 4ah leads to a regioselective and short synthesis of 2-aroylbenzofurans 2ah. The WolffKishner reduction of the latter yielded a series of substituted 2-ben
Potent CYP19 (aromatase) 1-(benzofuran-2-yl)(phenylmethyl)pyridine, -imidazole, and -triazole inhibitors: Synthesis and biological evaluation
Saberi, Mohammed Reza,Vinh, Tai Ky,Yee, Sook Wah,Griffiths, B. J. Nathan,Evans, Peter J.,Simons, Claire
, p. 1016 - 1022 (2007/10/03)
The synthesis of a series of novel 1-[(benzofuran-2-yl)phenylmethyl]- pyridine, -imidazole, and -triazole derivatives is described. All the compounds were evaluated in vitro for inhibitory activity against aromatase (P450 AROM, CYP19), using hu
