30932-38-8

Basic information

• Product Name: Benzene, 1-[(phenylsulfonyl)methyl]-4-(trifluoromethyl)-
• CAS NO: 30932-38-8
• Molecular Formula: C14H11F3O2S
• Molecular Weight: 300.301
• Mol File: 30932-38-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(phenylsulfonyl)methyl]-4-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(phenylsulfonyl)methyl]-4-(trifluoromethyl)-(30932-38-8)
• EPA Substance Registry System: Benzene, 1-[(phenylsulfonyl)methyl]-4-(trifluoromethyl)-(30932-38-8)

Safety Data

• Hazardous Substances Data: 30932-38-8(Hazardous Substances Data)

Upstream product

• 30932-37-7 phenyl(4-(trifluoromethyl)benzyl)sulfane 
• 71740-33-5 N,N-dimethyl-1-(4-(trifluoromethyl)phenyl)methanamine 
• 1416982-09-6 N,N,N-trimethyl-1-(4-(trifluoromethyl)phenyl)methanaminium trifluoromethanesulfonate 
• 873-55-2 sodium benzenesulfonate 
• 402-49-3 4-bromomethyltrifluoromethylbenzene 
• 349-95-1 4-(trifluoromethyl)benzylic alcohol 

Downstream Products

• 530158-39-5 4-[2-(4-trifluoromethylphenyl)-2-(phenylsulfonyl)vinyl]benzaldehyde 
• 32857-62-8 4-Trifluoromethylphenylacetic acid 
• 1149-56-0 (E)-4-trifluoromethylstilbene 
• 1609277-66-8 di(4-trifluoromethylphenyl)methyl phenyl sulfone 
• 1609277-65-7 phenyl(4-trifluoromethylphenyl)methyl phenyl sulfone 
• 1609277-76-0 tris(4-trifluoromethylphenyl)methane 
• 1609277-75-9 [4-(N,N-dimethylamino)phenyl]phenyl(4-trifluoromethylphenyl)methane 
• 1057717-21-1 4-[2-benzenesulfonyl-1-(4-dimethylaminophenyl)-2-(4-trifluoromethylphenyl)ethyl]-2,6-di-tert-butylphenol 

Relevant articles and documents

Cu2O-catalyzed C–S coupling of quaternary ammonium salts and sodium alkane-/arene-sulfinates

A new protocol for the synthesis of (enantioenriched) benzylic sulfones via the Cu2O-catalyzed C–S bond cross coupling of alkane-/arene-sulfinates and (enantioenriched) benzylic quaternary ammonium salts has been developed. The product benzylic sulfones were obtained in good to high yields (75–96%). Chiral arylmethyl sulfones with high enantiomeric excess (90–94% ee) were also synthesized in the presence of Cu2O and 1,1′-bis-(diphenylphosphino)ferrocene (dppf).

Manganese-Catalyzed Acceptorless Dehydrogenative Coupling of Alcohols with Sulfones: A Tool to Access Highly Substituted Vinyl Sulfones

The development of first-row-transition-metal catalysts that can match with the reactivities of the noble metals is considered to be challenging yet very much a desirable goal in homogeneous catalysis. It has become even more fascinating to develop processes where these metals show a unique reactivity and selectivity than their higher congeners. Herein, we report on the catalytic activity of a pincer complex of the abundant earth metal manganese for an unprecedented acceptorless dehydrogenative coupling of alkyl sulfones with alcohols. Thus, highly functionalized vinyl sulfones were obtained in moderate to good yields. Both benzylic and aliphatic alcohols could be utilized, and several functional groups including bromides and iodides are tolerated under the reaction conditions. The reaction is environmentally benign, producing dihydrogen and water as byproducts. Preliminary mechanistic experiments involving kinetic, deuterium-labeling, and NMR experiments were performed.

Expedient Diels-Alder assembly of 4-aryl-4-phenylsulfonyl cyclohexanones

The efficient preparation of 4-aryl-4-phenylsulfonyl cyclohexanones, containing a quaternary sulfone-bearing carbon centre, is described. Their synthesis proceeds in 38-78% overall yield by way of three steps: (i) sulfinate alkylation; (ii) methylenation;