309735-05-5Relevant academic research and scientific papers
BENZIMIDAZOLE INHIBITION OF BIOFILM FORMATION
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Paragraph 0095, (2014/02/15)
The various embodiments relate to a compound comprising: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are
Ligand-based design of a potent and selective inhibitor of cytochrome P450 2C19
Foti, Robert S.,Rock, Dan A.,Han, Xiaogang,Flowers, Robert A.,Wienkers, Larry C.,Wahlstrom, Jan L.
experimental part, p. 1205 - 1214 (2012/04/04)
A series of omeprazole-based analogues was synthesized and assessed for inhibitory activity against CYP2C19. The data was used to build a CYP2C19 inhibition pharmacophore model for the series. The model was employed to design additional analogues with inh
