309755-07-5

Upstream product

• 177742-46-0 (4R,5R)-5-formyl-2,2-dimethyl-4-pentyl-1,3-dioxane 
• 111061-31-5 1-phenoxy-1-trimethylsilyloxyethene 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 309754-98-1 (S)-3-((4R,5S)-2,2-Dimethyl-4-pentyl-[1,3]dioxan-5-yl)-3-hydroxy-propionic acid phenyl ester 

Downstream Products

• 309755-06-4 (2S,4R)-1-[(4R,6R)-6-(2-Benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-5-{(4S,6S)-6-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-((4R,5R)-2,2-dimethyl-4-pentyl-[1,3]dioxan-5-yl)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-pentane-2,4-diol 

Relevant academic research and scientific papers

An effective extension of the polyacetate chain in the polyene macrolide antibiotic filipin III, based on chiral oxazaborolidinone-promoted asymmetric aldol reactions

The enantioselective construction of the iterative polyacetate unit 3 in filipin III has been accomplished, essentially by an aldol strategy based on chiral oxazaborolidinone-promoted asymmetric aldol reactions. (C) 2000 Elsevier Science Ltd.