309757-71-9

Usage

Uses

Used in Pharmaceutical Synthesis:
(S)-3-(3'-FLUOROPHENYL)ALANINE T-BUTYL ESTER is used as a key intermediate in the synthesis of pharmaceuticals for its unique structural properties that can contribute to the development of novel drugs with improved therapeutic effects.
Used in Peptide Synthesis:
In the field of peptide synthesis, (S)-3-(3'-FLUOROPHENYL)ALANINE T-BUTYL ESTER serves as a building block for the creation of custom peptides with specific biological activities, tailored for research and potential therapeutic applications.
Used in Amino Acid Derivative Research:
(S)-3-(3'-FLUOROPHENYL)ALANINE T-BUTYL ESTER is utilized as a subject of study in research focused on amino acid derivatives, exploring their biological activities and potential uses in medicine and other industries.
Used in Chemical and Biochemical Research:
(S)-3-(3'-FLUOROPHENYL)ALANINE T-BUTYL ESTER is also used in chemical and biochemical research to investigate the effects of structural modifications on the properties and functions of amino acids, providing insights into the development of new compounds and materials.

Upstream product

• 309757-69-5 tert-butyl (3R,αS)-3-(3-fluorophenyl)-3-(N-α-methyl-4-methoxybenzylamino)propanoate 
• 456-48-4 3-Fluorobenzaldehyde 
• 277745-38-7 (E)-3-(3-fluorophenyl)acrylic acid tert-butyl ester 
• 27784-76-5 tert-butyl diethylphosphonoacetate 
• 277745-39-8 tert-butyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-(3'-fluorophenyl)propanoate 
• 309757-67-3 tert-butyl (3R,αS)-3-(3-fluorophenyl)-3-(N-benzyl-N-α-methyl-4-methoxybenzylamino)propanoate 

Downstream Products

• 500789-04-8 (R)-3-(tert-butoxycarbonylamino)-3-(3-fluorophenyl)propanoic acid 

Relevant academic research and scientific papers

BICYCLIC-PYRIMIDINEDIONE COMPOUNDS

The present invention provides novel bicyclic pyrimidinedione compounds that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds is described, as well as methods for treating HCM and other forms of heart disease.

Asymmetric synthesis of β-fluoroaryl-β-amino acids

The conjugate addition of lithium (R)-N-benzyl-N-(α-methylbenzyl) amide to a range of β-fluoroaryl-α,β-unsaturated esters gave the corresponding β-amino esters with high diastereoselectivity and in good isolated yields. Sequential treatment of the resulta

Asymmetric synthesis of β-haloaryl β-amino acid derivatives

Lithium N-benzyl-N-α-methyl-4-methoxybenzylamide may be employed as a homochiral ammonia equivalent for the synthesis of homochiral β-haloaryl β-amino acid derivatives via a strategy involving its conjugate addition to α,β-unsaturated β-haloaryl acceptors and subsequent oxidative deprotection with ceric ammonium nitrate.

The asymmetric synthesis of β-haloaryl-β-amino acid derivatives

Lithium N-benzyl-N-α-methyl-4-methoxybenzylamide is employed as a homochiral ammonia equivalent for the asymmetric synthesis of β-haloaryl-β-amino acid derivatives using a conjugate addition/oxidative deprotection strategy.