309761-12-4

Upstream product

• 312329-70-7 4-(3-hydroxyphenyl)-trans-3,4-dimethylpiperidine 
• 111-25-1 1-bromo-hexane 

Downstream Products

• 312329-60-5 N-hexyl-trans-3,4-dimethyl-4-(3-trifluoromethanesulfonyloxyphenyl)piperidine 
• 320601-36-3 1-Hexyl-3,4-dimethyl-4-(3-(1H-tetrazol-5-yl)phenyl)piperidine 
• 312329-54-7 4-(3-acetylphenyl)-1-hexyl-3,4-dimethylpiperidine 
• 312329-17-2 1-hexyl-3,4-dimethyl-4-(3-cyanophenyl)piperidine 

Relevant academic research and scientific papers

New 4-arylpiperidine derivatives for the treatment of pruritus

There is provided a compound of formula I, wherein Het1, R1, R2, R3, X and n have meanings given in the description, which are useful in the prophylaxis and in the treatment of diseases mediated by opiate receptors, such as pruritus.

Compounds useful in therapy

There is provided a compound of formula I, wherein R1, R2, R3 and Y have meanings given in the description, which are useful in the prophylaxis and in the treatment of pruritus.

Compounds useful in therapy

There is provided a compound of formula I, wherein Het1, T, X, R1, R2and R3have meanings given in the description, which are useful in the prophylaxis and in the treatment of diseases mediated by opiate receptors, such as pruritus.

4-arylpiperidine derivatives for the treatment of pruritus

There is provided a compound of formula I, wherein R1, R2, R3, X and Y have meanings given in the description, which are useful in the prophylaxis and in the treatment of pruritus.

4-arylpiperidine derivatives for the treatment of pruritus

There is provided a compound of formula I, wherein R1, R2, R3 and Y have meanings given in the description, which are useful in the prophylaxis and in the treatment of pruritus.

4-arylpiperidine derivatives for the treatment of pruritus

There is provided a compound of formula I, wherein Het1, R1, R2, R3, X and n have meanings given in the description, which are useful in the prophylaxis and in the treatment of diseases mediated by opiate receptors, such as pruritus.