309925-20-0

Basic information

• Product Name: N-(6-nitrobenzo[d]thiazol-2-yl)-3-(trifluoromethyl)benzamide
• Synonyms: N-(6-nitrobenzo[d]thiazol-2-yl)-3-(trifluoromethyl)benzamide
• CAS NO: 309925-20-0
• Molecular Weight: 367.308
• Mol File: 309925-20-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(6-nitrobenzo[d]thiazol-2-yl)-3-(trifluoromethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(6-nitrobenzo[d]thiazol-2-yl)-3-(trifluoromethyl)benzamide(309925-20-0)
• EPA Substance Registry System: N-(6-nitrobenzo[d]thiazol-2-yl)-3-(trifluoromethyl)benzamide(309925-20-0)

Safety Data

• Hazardous Substances Data: 309925-20-0(Hazardous Substances Data)

Upstream product

• 6285-57-0 2-amino-6-nitrobenzothiazole 
• 2251-65-2 3-(Trifluoromethyl)benzoyl chloride 

Relevant articles and documents

Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide

Head group analogues of the antibacterial and antiparasitic drug nitazoxanide (NTZ) are presented. A library of 39 analogues was synthesized and assayed for their ability to suppress growth of Helicobacter pylori, Campylobacter jejuni, Clostridium difficile and inhibit NTZ target pyruvate:ferredoxin oxidoreductase (PFOR). Two head groups assayed recapitulated NTZ activity and possessed improved activity over their 2-amino-5-nitrothiazole counterparts, demonstrating that head group modification is a viable route for the synthesis of NTZ-related antibacterial analogues.