31003-03-9Relevant academic research and scientific papers
α-Aminophosphonates: Effective carriers for the membrane transport of biorelevant species
Antipin, Igor S.,Stoikov, Ivan I.,Konovalov, Alexander I.
, p. 347 - 350 (2007/10/03)
The novel lipophilic α-aminophosphonates were synthesized by the Kabachnik-Fields reaction. These compounds exhibited remarkable selectivity as carriers for the membrane transport of the biorelevant species such as α-amino and α-hydroxy acids.
Membrane extraction of organic compounds 2. * transport of glycolic acid induced by α-aminophosphonates: Kinetic study
Antipin,Stoikov,Repeikov,Konovalov
, p. 1697 - 1701 (2007/10/03)
New lipophilic α-aminophosphonates containing cyclic or acyclic alkyl substituents at the carbon atom in the a position were synthesized by the Kabachnik-Fields reaction. Studies of the obtained compounds as carriers for transport of glycolic acid through polymer-supported liquid membranes demonstrated that the flux of glycolic acid through the membrane depends on the lipophilicity and the presence of substituents at the α-C atom of aminophosphonate. The structures of a number of α-aminophosphonate - glycolic acid complexes were calculated by the semiempirical PM3 method.
