31003-06-2Relevant academic research and scientific papers
Synthesis of some new cyclic aminophosphonates and their physiological activities
Wieczorek,Gancarz,Bielecki,Grzys,Sarapuk
, p. 119 - 128 (2007/10/03)
The synthesis of 19 newly synthesized cyclic aminophosphonic acid derivatives was described and their biological activity studied. It was found, as in the case of the previously described series of acyclic analogues, that the phytotoxicity of the compounds, tested on aquatic plant Spirodela oligoryhiza depended mainly on their Hydrophobic parameters. The most pronounced phytotoxicity, the measure of which was concentration of aminophosphonates causing 50% inhibition of plant growth (EC50), exhibited compounds with not too long hydrocarbon substituent on the nitrogen atom (8-10 carbon atoms) and branched propyl groups on the phosphorus atom. The test had preliminary character and permitted to eliminate the less promising compounds for further studies.
