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17α-dehydroxyprednisolone is an important intermediate in the synthesis of various corticosteroids, which are a class of steroid hormones that have potent anti-inflammatory and immunosuppressive properties. This chemical is a derivative of prednisolone, with the removal of a hydroxyl group at the 17α position, which significantly alters its biological activity. 17α-dehydroxyprednisolone is used as a precursor in the production of several corticosteroid drugs, such as prednisone and dexamethasone, which are widely prescribed for treating conditions like asthma, rheumatoid arthritis, and other autoimmune diseases. The chemical's structure and properties make it a crucial component in the pharmaceutical industry for the development of life-saving medications.

3103-17-1

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3103-17-1 Usage

Type of compound

Synthetic corticosteroid

Derivation

Derived from prednisolone

Role in production

Intermediate in the production of various corticosteroid medications

Medical use

Treats a wide range of inflammatory and immune-related conditions

Similar properties

Has similar properties to prednisolone, including anti-inflammatory and immunosuppressant effects

Receptor affinity

High affinity for glucocorticoid receptors

Gene transcription

Modulates gene transcription related to various physiological processes

Specific applications

Notably used in the synthesis of pharmaceuticals for the treatment of conditions such as asthma, autoimmune diseases, and allergies
This list provides a concise overview of the key characteristics and uses of 17α-dehydroxyprednisolone, as described in the material.

Check Digit Verification of cas no

The CAS Registry Mumber 3103-17-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,0 and 3 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3103-17:
(6*3)+(5*1)+(4*0)+(3*3)+(2*1)+(1*7)=41
41 % 10 = 1
So 3103-17-1 is a valid CAS Registry Number.

3103-17-1Downstream Products

3103-17-1Relevant academic research and scientific papers

Anti-inflammatory carboxy pregnane derivatives

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, (2008/06/13)

Compounds of the formula: STR1 wherein one X is COOR, CH2 COOR, CH(COOR)2, CONHR, CH2 CONHR, or CN remaining X's are H, F, CH3, OH, COOR, CH2 COOR, CH(COOR)2, CONHR, CH2 CONHR, or CN; Y is STR2 R is H, alkyl of 1-5 carbon atoms, or benzyl; R1 is CH2 OR3, COOR, or CONHR; R2 is H, OR3, or BR; R3 is H, COR4, or tetrahydropyranyl; R4 is alkyl of 1-5 carbon atoms or benzyl; R5 is H or COR4 ; represents a single or double bond; represents α-position, β-position, or a mixture of α- and β-positions; and --- represents α-position; and methods for preparing the same.

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