31039-63-1Relevant academic research and scientific papers
The first enantioselective total synthesis of lantalucratin C and determination of its absolute configuration
Ogata, Tokutaro,Tanaka, Manami,Ishigaki, Momoe,Shimizu, Maki,Nishiuchi, Arisa,Inamoto, Kiyofumi,Kimachi, Tetsutaro
, p. 6672 - 6680 (2015)
Described here is the first enantioselective total synthesis of lantalucratin C, which was isolated from the rainforest plant Lantana involucrata, and which possesses anti-tumor activity. The OH group on the aromatic ring was systematically introduced by
Palladium(II)-Catalyzed Reaction of Lawsones and Propargyl Carbonates: Construction of 2,3-Furanonaphthoquinones and Evaluation as Potential Indoleamine 2,3-Dioxygenase Inhibitors
Feng, Xi,Qiu, Xiaqiu,Huang, Huidan,Wang, Jubo,Xu, Xi,Xu, Pengfei,Ge, Ruijia,Liu, Xiaojin,Li, Zhiyu,Bian, Jinlei
, p. 8003 - 8010 (2018/06/22)
An efficient reaction utilizing propargyl carbonates through Claisen rearrangement to synthesize furanonaphthoquinones is described. The remarkable transformation exhibits excellent functional group tolerance, affording the target furanonaphthoquinones in
Unusual, chemoselective etherification of 2-hydroxy-1,4-naphthoquinone derivatives utilizing alkoxymethyl chlorides: Scope, mechanism and application to the synthesis of biologically active natural product (±)-lantalucratin C
Ogata, Tokutaro,Yoshida, Tomoyo,Shimizu, Maki,Tanaka, Manami,Fukuhara, Chie,Ishii, Junko,Nishiuchi, Arisa,Inamoto, Kiyofumi,Kimachi, Tetsutaro
, p. 1423 - 1432 (2017/02/15)
A novel etherification of 2-hydroxy-1,4-naphthoquinone derivatives with alkoxyalkyl chlorides and hydride bases is described. Precise study of the conditions and substrate scope suggested that the reaction occurs specifically in the molecule having a 2-hydroxy-1,4-benzoquinone skeleton. A chemoselective O-methylation reaction was achieved to afford a synthetically important intermediate, which offered easy access to a natural product possessing anti-tumor activity.
Fused quinonic compounds
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, (2014/02/15)
A compound having the formula (I): for use in treating disease; a composition comprising said fused quinonic compound of formula (I) and at least one pharmaceutically acceptable carrier; as well as a method of modulating a Janus Kinase-Signal Transduction
FUSED QUINONIC COMPOUNDS
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Page/Page column 49; 50, (2014/02/16)
A compound having the formula (I), for use in treating a disease; a composition comprising said fused quinonic compound of formula (I) and at least one pharmaceutically acceptable carrier; as well as a method of modulating a Janus Kinase-Signal Transducti
Biomimetic synthesis of antimalarial naphthoquinones
Malerich, Jeremiah P.,Maimone, Thomas J.,Elliott, Gregory I.,Trauner, Dirk
, p. 6276 - 6283 (2007/10/03)
The total synthesis of naphthoquinone natural products isolated from the Bignoniaceae plant family is described. Pinnatal, isopinnatal, sterekunthals A and B, pyranokunthones A and B, and anthrakunthone have been prepared along the lines of a biosynthetic
Method for dyeing keratinous fibres using a monohydroxyindole or dihydroxyindole and a non-oxidizing aromatic carbonyl derivative and dyeing agent
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, (2008/06/13)
The present invention relates to a method for dyeing keratinous fibers, characterized in that the following are applied to the fibers: a) a composition (A) containing, in a medium appropriate for dyeing, at least one monohydroxyindole or dihydroxyindole, this application being preceded or followed by the application of b) a composition (B) containing, in a medium appropriate for dyeing, at least one aromatic carbonyl derivative chosen from hydroxyacetophenones, hydroxybenzophenones, 2-hydroxy-1,4-benzoquinones, hydroxy-1,4-naphthoquinones,amino-1,4-naphthoquinones,hydroxy-9,10-anthraquinones and amino-9,10-anthraquinones. It also relates to the dyeing agents for carrying it out.
Reactivity of potassium superoxide in heterogeneous phase: Oxidation of naphthalenediols and hydroxylated naphthoquinones
De Min,Croux,Tournaire,Hocquaux,Jacquet,Oliveros,Maurette
, p. 1869 - 1882 (2007/10/02)
Oxidation of dihydroxynaphthalenes by potassium superoxide (KO2) in heterogeneous aprotic media yields mono- or dihydroxynaphthoquinones, depending on the relative position of the hydroxy groups on the naphthalene moiety. The reaction proceeds mainly at the solid-liquid interface and naphthoquinones can be obtained with good yields.
