31040-15-0 Usage
Uses
Used in Medicinal Chemistry:
6-Nitro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine is utilized as a key intermediate in the synthesis of biologically active molecules and pharmaceuticals. Its unique structure allows it to interact with various biological targets, modulating their activity and contributing to the development of new therapeutic agents.
Used in Drug Development:
In the pharmaceutical industry, 6-Nitro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine is employed for its potential in creating novel drugs. Its capacity to engage with biological targets makes it a promising candidate for further exploration and research aimed at developing innovative treatments for various diseases and conditions.
While the exact properties and biological activities of 6-Nitro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine have not been extensively studied, its role in medicinal chemistry and drug development highlights its potential for future advancements in therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 31040-15-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,0,4 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 31040-15:
(7*3)+(6*1)+(5*0)+(4*4)+(3*0)+(2*1)+(1*5)=50
50 % 10 = 0
So 31040-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H5N5O2/c7-6-8-5-2-1-4(11(12)13)3-10(5)9-6/h1-3H,(H2,7,9)
31040-15-0Relevant academic research and scientific papers
Oxidative cyclization of 1-(pyridin-2-yl)guanidine derivatives: A synthesis of [1,2,4]triazolo[1,5-a]pyridin-2-amines and an unexpected synthesis of [1,2,4]triazolo[4,3-a]pyridin-3-amines
Ishimoto, Kazuhisa,Nagata, Toshiaki,Murabayashi, Mika,Ikemoto, Tomomi
, p. 407 - 418 (2015/03/03)
Oxidative cyclization of 1-(pyridin-2-yl)guanidine derivatives using N-chlorosuccinimide and aqueous potassium carbonate has been investigated. Chlorination of 1-(5-nitropyridin-2-yl)guanidine by N-chlorosuccinimide in methanol followed by addition of aqueous potassium carbonate gave rise to cyclization and afforded 6-nitro-[1,2,4]triazolo[1,5-a]pyridin-2-amine in one-pot. In the course of studying the scope and limitation of the reaction, it was found that some of the examined 1-(pyridin-2-yl)guanidine derivatives gave not only the desired [1,2,4]triazolo[1,5-a]pyridin-2-amines but also unexpected [1,2,4]triazolo[4,3-a]pyridin-3-amine products. As plausible reaction mechanisms of this oxidative cyclization, diazirine formation and nitrene formation are presented.
