31040-76-3Relevant academic research and scientific papers
Rhenium(I)-catalyzed cyclization of silyl enol ethers containing a propargyl carboxylate moiety: Versatile access to highly substituted phenols
Saito, Kodai,Onizawa, Yuji,Kusama, Hiroyuki,Iwasawa, Nobuharu
supporting information; experimental part, p. 4716 - 4720 (2010/07/02)
Selective migration: The rhenium-catalyzed reaction of 2-siloxy-1-en-5-ynes containing an acyloxy substituent at the propargylic position gave highly substituted phenols in good yields (see scheme). Depending on the structure of the silyl enol ether, either nucleophilic addition of this moiety or 1,2acyloxy migration occurs to give two kinds of synthetically useful, substituted phenols. (Chemical Equation Presented)
BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS
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Page 159, (2010/02/08)
The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (1). Wherein Z, X, R1, R2, R3, and R4 are as described in specification.
CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS
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Page 159, (2010/02/08)
The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (I). Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.
