310416-49-0

Upstream product

• 65234-02-8 2-mercapto-3-p-methoxypheny-5,6-tetramethylenethieno[2,3-d]pyrimidin-4-one 
• 74-88-4 methyl iodide 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 
• 65233-90-1 N¹-(3-carbethoxy-4,5,6,7-tetrahydrobenzothien-2-yl)-N²-p-methoxyphenylthiourea 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 

Relevant academic research and scientific papers

COMPOUNDS, SCREENS, AND METHODS OF TREATMENT

The present invention features compounds of Formula (I), pharmaceutical compositions, methods of synthesis, and methods for treating diseases and conditions associated with cellular necrosis. Screening assays for identifying compounds useful for treating

Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5

Necrostatin-5 (Nec-5) is a novel potent small-molecule inhibitor of necroptosis structurally distinct from previously described Necrostatin-1 (Nec-1), and therefore, represents a new direction for the inhibition of this cellular caspase-independent necrot