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4-[(3-Hydroxy-4-methylphenyl)amino]-5-methoxypyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

310443-08-4

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310443-08-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 310443-08-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,0,4,4 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 310443-08:
(8*3)+(7*1)+(6*0)+(5*4)+(4*4)+(3*3)+(2*0)+(1*8)=84
84 % 10 = 4
So 310443-08-4 is a valid CAS Registry Number.

310443-08-4Downstream Products

310443-08-4Relevant academic research and scientific papers

Pyrrolotriazine inhibitors of kinases

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Page/Page column 69, (2008/06/13)

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

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