3107-21-9 Usage
Uses
Used in Chemical Synthesis:
1,2,3-Trichloro-5-fluorobenzene is used as an intermediate in the production of various agrochemicals and pharmaceuticals. Its unique structure allows for the synthesis of a wide range of compounds, making it an essential component in the chemical industry.
Used in Industrial Processes:
1,2,3-Trichloro-5-fluorobenzene is utilized as a solvent in various industrial processes. Its properties as a solvent contribute to the efficiency and effectiveness of these processes, further highlighting its importance in the chemical industry.
Used in Chemical Research:
Due to its unique chemical structure and properties, 1,2,3-Trichloro-5-fluorobenzene is also used in chemical research for the development of new compounds and the study of chemical reactions. Its versatility as a compound makes it a valuable tool for researchers in the field of chemistry.
Environmental and Health Considerations:
While 1,2,3-Trichloro-5-fluorobenzene has numerous applications in the chemical industry, it is also considered hazardous to human health and the environment. Therefore, it is crucial to follow proper handling and disposal procedures when working with 1,2,3-Trichloro-5-fluorobenzene. This includes using appropriate personal protective equipment, ensuring proper storage and disposal, and implementing safety measures to minimize the risk of exposure and environmental contamination.
Check Digit Verification of cas no
The CAS Registry Mumber 3107-21-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,0 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3107-21:
(6*3)+(5*1)+(4*0)+(3*7)+(2*2)+(1*1)=49
49 % 10 = 9
So 3107-21-9 is a valid CAS Registry Number.
3107-21-9Relevant academic research and scientific papers
Synthesis and Biological Evaluation of an Indazole-Based Selective Protein Arginine Deiminase 4 (PAD4) Inhibitor
Tjin, Caroline Chandra,Wissner, Rebecca F.,Jamali, Haya,Schepartz, Alanna,Ellman, Jonathan A.
supporting information, p. 1013 - 1018 (2018/10/02)
Protein arginine deiminase 4 (PAD4) is a calcium-dependent enzyme that catalyzes the conversion of arginine to citrulline within target proteins. Dysregulation of PAD4 has been implicated in a number of human diseases, including rheumatoid arthritis and other inflammatory diseases as well as cancer. In this study, we report on the design, synthesis, and evaluation of a new class of haloacetamidine-based compounds as potential PAD4 inhibitors. Specifically, we describe the identification of 4,5,6-trichloroindazole 24 as a highly potent PAD4 inhibitor that displays >10-fold selectivity for PAD4 over PAD3 and >50-fold over PAD1 and PAD2. The efficacy of this compound in cells was determined by measuring the inhibition of PAD4-mediated H4 citrullination in HL-60 granulocytes.
