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[5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid, also known as tenofovir, is a nucleotide analogue reverse transcriptase inhibitor derived from the chemical structure of adenine. It is characterized by its ability to inhibit the replication of certain viruses, particularly human immunodeficiency virus (HIV) and hepatitis B virus (HBV). Tenofovir exhibits its antiviral activity by blocking the enzyme reverse transcriptase, which is crucial for the viral replication process. This leads to a reduction in the viral load and helps in controlling the progression of the infection.

31077-38-0

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31077-38-0 Usage

Uses

Used in HIV/AIDS Treatment:
Tenofovir is used as an antiretroviral agent for the treatment of HIV/AIDS. It is employed to control the viral load and prevent the progression of the infection, thereby improving the quality of life and life expectancy of patients. The drug is often prescribed as part of a combination therapy, which includes other antiretroviral medications to enhance the treatment's effectiveness.
Used in Chronic Hepatitis B Treatment:
In addition to its use in HIV/AIDS treatment, tenofovir is also utilized in the treatment of chronic hepatitis B. It helps in managing the viral load and reducing the risk of liver damage, cirrhosis, and liver cancer associated with chronic HBV infection.
Used in Combination Therapies:
Tenofovir is often combined with other antiretroviral drugs to form highly active antiretroviral therapy (HAART) for HIV/AIDS patients. This combination approach aims to target the virus from multiple angles, reducing the likelihood of drug resistance and improving treatment outcomes.
Used in Tablet Formulations:
Tenofovir is available in tablet formulations, making it a convenient and accessible option for patients requiring antiretroviral therapy. The tablets can be easily incorporated into a daily medication regimen, facilitating adherence to the treatment plan.
Used in Drug Delivery Systems:
To enhance the bioavailability, delivery, and therapeutic outcomes of tenofovir, various drug delivery systems have been developed. These systems aim to improve the drug's pharmacokinetics and minimize potential side effects, such as kidney and bone toxicity.

Check Digit Verification of cas no

The CAS Registry Mumber 31077-38-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,0,7 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 31077-38:
(7*3)+(6*1)+(5*0)+(4*7)+(3*7)+(2*3)+(1*8)=90
90 % 10 = 0
So 31077-38-0 is a valid CAS Registry Number.

31077-38-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name [5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

1.2 Other means of identification

Product number -
Other names Ara-AMP

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:31077-38-0 SDS

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