31089-97-1

Upstream product

• 28043-10-9 methyl 2,6,6-trimethyl-cyclohex-2-en-1-yl carboxylate 
• 121135-36-2 2,6,10-trimethylundecan-(5E)-2,5,9-trien-4-one 
• 127-41-3 alpha-ionone 
• 917-54-4 methyllithium 

Relevant academic research and scientific papers

General Synthesis of Ketones from Carboxylic Esters and Carboxamides by Use of Mixed Organolithium-Magnesium Reagents: Syntheses of Artemisia Ketone

The novel reagents formed by combination of Grignard reagents (RMgX) with lithium diisopropylamide (LDA) convert non-enolizable carboxylic esters or carboxamides into ketones which are protected from further reaction by their in situ conversion into enolates.These enolates can be trapped with electrophiles such as Me3SiCl and allyl bromide.The scope of this Grignard mono-addition is illustrated by two direct synthesis of artemisia ketone (14).

Alkenoyl-cyclohexadienes

New cycloaliphatic unsaturated ketones and their use as perfuming and odour-modifying agents in the manufacture of perfumes and perfumed products, and as flavouring and taste-modifying agents in the preparation of foodstuffs in general and imitation flavours for foodstuffs, beverages, animal feeds, pharmaceutical preparations and tobacco products. Methods for the preparation of said cycloaliphatic unsaturated ketones.