31108-45-9

Upstream product

• 25209-80-7 2,3-dichloropropyl phenylcarbamate 
• 103-71-9 phenyl isocyanate 
• 116-09-6 hydroxy-2-propanone 
• 107-19-7 propargyl alcohol 
• 31108-44-8 4-methylen-3-phenyl-1,3-oxazolidin-2-one 

Downstream Products

• 52512-34-2 3t-benzoyl-6a-methyl-2,6-diphenyl-(3ar,6ac)-tetrahydro-oxazolo[5,4-d]isoxazol-5-one 
• 52512-32-0 6a-methyl-2,6-diphenyl-3ξ-(2,4,6-trimethyl-phenyl)-(3ar,6ac)-tetrahydro-oxazolo[5,4-d]isoxazol-5-one 
• 56412-91-0 4H-5,13-dimethyl-1-phenyl-1-aza-3,7-dioxa-dicyclopenta--quinolin-2,8-diene 
• 56412-92-1 4-methyl-3-phenyl-5-<4'-methyl-3'-phenyl-oxazolidin-2'-on-4'-il>-Δ⁴-oxazolin-2-one 
• 76089-70-8 4'-Bromomethyl-4-methyl-3,3'-diphenyl-4,5-dihydro-3H,3'H-[4,5']bioxazolyl-2,2'-dione 
• 52512-38-6 5-benzoyl-4-methyl-3-phenyl-3H-oxazol-2-one 
• 52512-36-4 5-(anilino-phenyl-methyl)-4-hydroxy-4-methyl-3-phenyl-oxazolidin-2-one 
• 1167438-88-1 4-methyl-5-(3-oxobutyl)-N-phenyl-4-oxazolidin-2-one 
• 52512-30-8 6a-methyl-2,3t,6-triphenyl-(3ar,6ac)-tetrahydro-oxazolo[5,4-d]isoxazol-5-one 

Relevant academic research and scientific papers

A single-step synthesis of 4-oxazolin-2-ones and their use in the construction of polycyclic structures bearing quaternary stereocenters

A new method for the synthesis of 4-oxazolin-2-ones by a one-pot MW-promoted condensation of a-ketols and isocyanates is reported. An alternative thermal approach using the same starting materials is also described. These cyclic enamides were efficient nucleophiles, reacting with Michael acceptors and prenyl bromide to give a variety of polycyclic structures bearing one or two quaternary stereocenters. The selectivity of the products depended on the reaction conditions and on the electrophile used. Wiley-VCH Verlag GmbH & Co. KGaA.

Regioselective 1,3-dipolar cycloaddition reactions of 4-methylene-2- oxazolidinones with benzonitrile oxide

Substituted 4-methylene-2-oxazolidinones were prepared in two steps by cyclizing O-propargyl carbamates, which in turn were prepared from propargyl alcohols and phenyl isocyanate. The 4-methylene-2-oxazolidinones underwent a 1,3-dipolar cycloaddition reac

Regiospecific Introduction of Amino-alkene Functionality into 1,2,3-Triols, 1,3-Dihalogenopropan-2-ols, and 2,3-Dihalogenopropanols promoted by Fluoride Anion

Regiospecific transformations of 1,2,3-triol, 1,3-dihalogenopropan-2-ol, and 2,3-dihalogenopropanol derivatives into oxazolidin-2-ones and/or oxazol-2(3H)-ones promoted by fluoride anion are described.