3111-50-0Relevant academic research and scientific papers
A novel water-soluble highly selective “switch-on” ionic liquid-based fluorescent chemi-sensor for Ca(II)
Elshaarawy, Reda F.M.,Ali, Reham,Saleh, Sayed M.,Janiak, Christoph
, p. 308 - 315 (2017)
A novel chemi-sensor involve new bis-ionic Schiff base sensor (BISBS), N,N′-bis-[5-((2,4-lutidiniumchloride)methylene)-3-methoxysalicylidene]-R,R-1,2-cyclohexanediimine, has been synthesized and characterized. BISBS chemi-sensor was designed based on internal charge transfer (ICT) fluorescence mechanism. This new water soluble chemi-sensor provides great selectivity fluorescence detection for Ca(II) ions in an important physiological pH range. Moreover, the interaction of Ca(II) with the deprotonated BISBS to produce a metal-ligand complex with a ratio of (1: 1) accompanying with an enhancement in the intensity of emission band located at 502?nm. Fluorescence switching-on during the chemical interaction between BISBS and Ca(II) ions is very easily noticed with naked eye, but other metal cations such as alkali, alkaline earth and transition metal don't give any fluorescence changes. The novel developed BISBS sensor successively offers low limit of detection (LOD) 1.5?nM and fast tracing of Ca(II) in the physiological pH?7.6. Thus BISBS may provide a novel auspicious methodology for detection calcium cations in the environmental and biological samples.
Recycling Oryza sativa wastes into poly-imidazolium acetic acid-tagged nanocellulose Schiff base supported Pd nanoparticles for applications in cross-coupling reactions
Elshaarawy, Reda F. M.,Yahya, Rana
, (2021/12/22)
A green and sustainable heterogeneous nanocatalyst for the Suzuki reaction was fabricated by refining rice straw to ionic nanocellulose Schiff base (NCESB) which was employed for bio-reduction of Pd(II) into Pd nanoparticles (Pd NPs) and immobilization of these NPs to fabricate the desired nanocatalyst (NCESB@Pd). The TEM image revealed well-dispersed PdNPs with sizes of 5–23 nm. The new nanocatalyst displayed amazing activity in catalyzing coupling reactions of a wide range of halobenzenes with phenylboronic acid at 50 °C (reaction time 15–60 min) and even at room temperature (reaction time 120 min). The NCESB@Pd nanocatalyst exhibited excellent recyclability (up to five catalytic runs) without a significant loss of its activity or identity. Therefore, the new ionic nanocatalyst may open a new window for a novel generation of ionic low-cost green and highly effective nanocatalysts for organic transformation reactions.
Synthesis and molecular docking of hybrids ionic azole Schiff bases as novel CDK1 inhibitors and anti-breast cancer agents: In vitro and in vivo study
Abdelghany, Yasmin M.,Abdelhamid, Moustafa S.,Elshaarawy, Reda F. M.,Serag, Waleed M.,Zahran, Faten
, (2021/07/19)
Three new hybrid ionic vanillyl-azole-Schiff bases (IVASBs) have synthesized and their antitumor performances were assessed in vitro against MCF-7 cells and in vivo against Ehrlich solid tumor (EST). The high binding energy score of IVASB3?CDK1 (?3.43 kca
A ratiometric and selective fluorescent chemosensor for Ca(II) ions based on a novel water-soluble ionic Schiff-base
Saleh, Sayed M.,Ali, Reham,Elshaarawy, Reda F. M.
, p. 68709 - 68718 (2016/08/05)
A new, simple and water-soluble chemosensor, based on the ionic Schiff-base (ISB), 1-(4-hydroxy-3-((2-mercaptophenylimino)methyl)-5-methoxybenzyl)-4-methoxypyridiniumchloride (3), was synthesized and applied to fluorescently sense Ca(ii) ions. This fluore
Directed Synthesis of Translationally Isomeric -Catenanes
Rissler, Klaus,Schill, Gottfried,Fritz, Hans,Vetter, Walter
, p. 1374 - 1399 (2007/10/02)
In a multi-step reaction sequence the tetrahydroxymetacyclophane 12c is synthesized.Acetalisation with 1,25-dichloro-13-pentacosanone followed by nitration and reduction afforded the diamine 13c.By cyclization of this compound in 2-pentanol with sodium carbonate and sodium iodide under high dilution conditions the monomeric products 16, 17, and 18 are obtained in yields of 21.4, 7.7, and 0,9percent, respectively.On the basis of mass, 13C NMR and 1H NMR spectra the structure of these compounds is discussed.Starting from the precatenane 16 the -catenanes 25a,b,c and 26a,b,c are obtained in a multi-step reaction sequence.The structure of these compounds is confirmed by mass, 13C NMR, and 1H NMR spectroscopic investigations.
