311323-36-1

Upstream product

• 36646-78-3 3-(p-tolylamino)-5,5-dimethylcyclohex-2-enone 
• 1122-91-4 4-bromo-benzaldehyde 
• 109-77-3 malononitrile 
• 106-49-0 p-toluidine 
• 126-81-8 dimedone 

Relevant academic research and scientific papers

Hexamethylenetetramine-based ionic liquid anchored onto the metal–organic framework MIL-101(Cr) as a superior and reusable heterogeneous catalyst for the preparation of hexahydroquinolines

Regarding the significance of medicinal and pharmacological sciences, we explored one-pot multicomponent reaction of aromatic aldehydes, aryl amines, malononitrile and dimedone in the presence of HMTA-BAIL@MIL-101 (Cr) as a novel, stable and strong catalyst. The remarkable features of this approach are good to excellent yields (92–98%), short reaction times (10–20?min), low catalyst loading, reusability and stability of the catalyst. The prepared hexamethylenetetramine-based ionic liquid/MIL-101(Cr) composite was identified via FE-SEM, XRD, EDS, TGA, BET and FT-IR techniques.

Study of the catalytic activity of Zr(HPO4)2 in the synthesis of hexahydroquinoline derivatives under solvent-free conditions

2-Amino-7,7-dimethyl-5-oxo-1,4-diaryl-1,4,5,6,7,8-hexahydroquinoline-3- carbonitrile derivatives were synthesized by the one-pot four-component reaction of aromatic aldehydes, malononitrile, dimedone and arylamines in the presence of Zr(HPO4)s

Eco-friendly and ingenious multicomponent synthesis of N-arylquinolines using DABCO/TEAB in water

An easy, improved, and environmentally benign synthesis of N-arylquinolines is reported via one-pot multicomponent reaction of aromatic aldehydes, active methylene compounds and 3-arylamino-5,5-dimethylcyclohex-2-enone utilizing catalytic amount of combin

DBU-catalyzed expeditious and facile multicomponent synthesis of N-arylquinolines under microwave irradiation

N-Arylquinoline derivatives are obtained in excellent yields by a rapid, easy, and efficient one-pot multicomponent reaction of aromatic aldehydes, 3-arylamino-5,5-dimethylcyclohex-2-enone, and active methylene compounds utilizing 1,8-diazabicyclo[5.4.0]u

Three-component green synthesis of N-arylquinoline derivatives in ionic liquid [Bmim+][BF4-]: reactions of arylaldehyde, 3-arylamino-5,5-dimethylcyclohex-2-enone, and active methylene compounds

Three series of N-arylquinoline derivatives were synthesized by the three-component reactions of arylaldehyde, 3-arylamino-5,5-dimethylcyclohex-2-enone, and active methylene compounds including malononitrile, meldrum's acid, and 1,3-indenedione in ionic l