3115-05-7 Usage
Originator
Bilibyk,Byk Gulden
Uses
Diagnostic aid (radiopaque medium, cholecystographic).
Manufacturing Process
1013.2 g 3-amino-2,4,6-triiodobenzoyl chloride are dissolved in a minimum
amount of hot dioxane and caused to flow into 700.6 g molten methyl β-
anilinopropionate with stirring. After the ensuing exothermic reaction has
gradually terminated the reaction mixture is heated on a steam bath for about
3 h and while boiling hot has then methanol and methanolic 3 N HCl added
thereto, where after it is cooled. The precipitated solids are separated and
washed with ether. 953.0 g methyl β-N-(3-amino-2,4,6-triiodobenzoyl)-
phenylaminopropionate are obtained having a melting paint of 156°-157°C.
Yield 74.2% of theoryThe methyl ester may be precipitated as the free acid by dissolving in
dioxane, addition of 3.15 N methanolic sodium hydroxide solution, pouring the
resulting reaction mixture in water, and acidulating the solution with 6 N HCl.
After separation and drying, 553.6 g β-N-(3-amino-2,4,6-triiodobenzoyl)-
phenylaminopropionic acid having a melting point of 133°-134.5°C are
obtained from 571.0 g methyl ester. Overall yield 73.46% of theory.
Brand name
Osbil (Mallinckrodt).
Therapeutic Function
Diagnostic aid
Safety Profile
Moderately toxic by ingestion andintravenous routes. When heated to decomposition itemits very toxic fumes of I- and NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 3115-05-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,1 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3115-05:
(6*3)+(5*1)+(4*1)+(3*5)+(2*0)+(1*5)=47
47 % 10 = 7
So 3115-05-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H13I3N2O3/c17-10-8-11(18)15(20)14(19)13(10)16(24)21(7-6-12(22)23)9-4-2-1-3-5-9/h1-5,8H,6-7,20H2,(H,22,23)
