31171-41-2Relevant academic research and scientific papers
Synthesis, antibacterial and antioxidant properties of pyrazolylpyridazines
Ather, Abdul Qayuum,Chaudhry, Faryal,Khan, Muhammad Naeem,Bueno, Eliana Aparecida Silicz,Khan, Misbahul Ain,Aslam, Noreen,Khan, Khalid M.,Athar, Muhammad Makshoof,Munawar, Munawar Ali,Ashraf, Muhammad,Ejaz, Syeda Abida
, p. 7743 - 7748 (2013/09/23)
A number of 6-chloro-3-(pyrazol-1′-yl) pyridazines were prepared from 3,6-dichloropyridazine via either reaction with hydrazine followed I by reaction with appropriate reagents to develop the pyrazole or through a nucleophilic reaction with a pyrazole. So
Synthesis and antihypertensive activity of novel 6-substituted-3-pyridazinylhydrazones
Szilagyi,Kasztreiner,Matyus,et al.
, p. 111 - 117 (2007/10/02)
The synthesis and hypotensive properties of a series of 6-substituted-3-pyridazinylhydrazones are described. The most active compound of the series. 1-(6-morpholino-3-pyridazinyl)-2-[1-(tert-butoxycarbonyl)-2-propylidene] hydrazine, is a more potent hypotensive agent than hydralazine with a longer duration of action and a lower toxicity. Structure-activity relationships are discussed.
