31171-48-9Relevant academic research and scientific papers
Synthesis and antihypertensive activity of novel 6-substituted-3-pyridazinylhydrazones
Szilagyi,Kasztreiner,Matyus,et al.
, p. 111 - 117 (2007/10/02)
The synthesis and hypotensive properties of a series of 6-substituted-3-pyridazinylhydrazones are described. The most active compound of the series. 1-(6-morpholino-3-pyridazinyl)-2-[1-(tert-butoxycarbonyl)-2-propylidene] hydrazine, is a more potent hypotensive agent than hydralazine with a longer duration of action and a lower toxicity. Structure-activity relationships are discussed.
