31181-88-1

Basic information

• Product Name: 2-BROMO-3-FLUOROPYRIDINE
• Synonyms: 5-FLUORO-2-FORMYLPYRIDINE;5-FLUORO-2-PYRIDINE CARBOXALDEHYDE;5-Fluoropyridine-2-carboxaldehyde;2-Pyridinecarboxaldehyde,5-fluoro-(9CI);2-Pyridinecarboxaldehyde,5-fluoro-;5-fluoropicolinaldehyde;5-Fluoro-2-formylpyridine, 5-Fluoropicolinaldehyde;5-Fluoropiconaldehyde
• CAS NO: 31181-88-1
• Molecular Formula: C₆H₄FNO
• Molecular Weight: 125.1
• Product Categories: PYRIDINE;pharmacetical;Aldehyde;Building Blocks
• Mol File: 31181-88-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 174℃
• Flash Point: 59℃
• Appearance: /
• Density: 1.269
• Vapor Pressure: 1.26mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.30±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-3-FLUOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-FLUOROPYRIDINE(31181-88-1)
• EPA Substance Registry System: 2-BROMO-3-FLUOROPYRIDINE(31181-88-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Hazardous Substances Data: 31181-88-1(Hazardous Substances Data)

Usage

General Description

2-BROMO-3-FLUOROPYRIDINE is a chemical compound with the molecular formula C5H3BrFN. It is a halogenated pyridine derivative, containing a bromine and a fluorine atom attached to the pyridine ring. 2-BROMO-3-FLUOROPYRIDINE is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is known for its reactivity and versatility in organic synthesis, making it a valuable tool for the production of various chemical compounds. Additionally, 2-BROMO-3-FLUOROPYRIDINE has been studied for its potential applications in materials science and medicinal chemistry due to its unique structural and chemical properties.

InChI:InChI=1/C6H4FNO/c7-5-1-2-6(4-9)8-3-5/h1-4H

Upstream product

• 327056-62-2 5-fluoropicolinonitrile 
• 41404-58-4 2-bromo-5-fluoropyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 802325-29-7 5-fluoro-2-hydroxylmethylpyridine 
• 107504-07-4 5-fluoro-pyridine-2-carboxylic acid methyl ester 
• 107504-08-5 5-fluoropicolinic acid 
• 148541-70-2 ethyl 5-fluoro-2-pyridinecarboxylate 

Downstream Products

• 915720-55-7 1-(5-fluoropyridin-2-yl)ethanol 
• 802325-29-7 5-fluoro-2-hydroxylmethylpyridine 
• 917760-91-9 (E)-3-(5-fluoropyridin-2-yl)acrylic acid hydrochloride 
• 1080060-00-9 5-[4-(cyclopropylsulfonyl)phenyl]-1-(5-fluoropyridin-2-yl)-6-(tetrahydro-2H-pyran-4-yl)hexane-1,4-dione 
• 1187680-31-4 C₁₃H₉NO₃ 
• 1365627-27-5 C₂₄H₂₄FN₅O 
• 1410040-99-1 N-{2-[3-(5-fluoropyridin-2-yl)-1,2-oxazol-5-yl]ethyl}-5-methyl-2-(2H-1,2,3-triazol-2-yl)benzamide 
• 1410039-24-5 N-ethyl-N-{2-[3-(5-fluoropyridin-2-yl)-1,2-oxazol-5-yl]ethyl}-5-methyl-2-(2H-1,2,3-triazol-2-yl)benzamide 
• 1149752-51-1 N-[(1R)-1-(5-fluoropyridin-2-yl)ethyl]-2-methylropane-2-sulfinamide 
• 1262511-72-7 2-[3-(4-chloro-phenyl)-5-methyl-pyrazol-1-yl]-4-(5-fluoro-pyridin-2-ylmethyl)cyclopentane-1,3-dione 
• 1262511-67-0 2-[3-(4-chloro-phenyl)-5-methyl-pyrazol-1-yl]-4-[1-(5-fluoro-pyridin-2-yl)-meth-(Z)-ylidene]cyclopentane-1,3-dione 
• 1262511-70-5 2-[3-(4-chloro-phenyl)-5-methyl-pyrazol-1-yl]-4-[1-(5-fluoro-pyridin-2-yl)-meth-(E)-ylidene]cyclopentane-1,3-dione 
• 892501-98-3 5 -(pyrrolidin-1-yl)picolinaldehyde 

Relevant articles and documents

NOVEL INDOLIZINE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

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The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor s

P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN

The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X