M2I-1 is a small molecule inhibitor that specifically targets the mitotic kinase, Mps1. It has demonstrated the ability to inhibit the growth of cancer cells by disrupting the spindle assembly checkpoint, leading to cell cycle arrest and apoptosis. Additionally, M2I-1 exhibits anti-inflammatory and anti-fibrotic properties, positioning it as a potential therapeutic agent for a range of diseases, including cancer, inflammatory disorders, and fibrosis. Ongoing research is focused on elucidating the mechanisms of action and exploring the clinical applications of M2I-1.
312271-03-7
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Basic information
- Product Name: M2I-1
- Synonyms: M2I-1;Mad2 inhibitor-1 (M2I-1)
- CAS NO:312271-03-7
- Molecular Formula: C19H24N4O4S
- Molecular Weight: 404.48326
- EINECS: N/A
- Product Categories: API
- Mol File: 312271-03-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: M2I-1(CAS DataBase Reference)
- NIST Chemistry Reference: M2I-1(312271-03-7)
- EPA Substance Registry System: M2I-1(312271-03-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 312271-03-7(Hazardous Substances Data)
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312271-03-7 Usage
Uses
Used in Cancer Therapy:M2I-1 is used as an anticancer agent for its ability to inhibit the growth of cancer cells by disrupting the spindle assembly checkpoint, resulting in cell cycle arrest and apoptosis. This makes it a promising candidate for the treatment of various types of cancer.
Used in Inflammatory Disorders:
M2I-1 is used as an anti-inflammatory agent due to its capacity to reduce inflammation, making it a potential treatment option for various inflammatory conditions.
Used in Fibrotic Diseases:
M2I-1 is used as an anti-fibrotic agent for its potential to mitigate fibrosis, offering a therapeutic approach for diseases characterized by excessive tissue scarring.
Used in Pharmaceutical Research:
M2I-1 serves as a valuable tool in pharmaceutical research for understanding the mechanisms of cell cycle regulation, mitotic kinase activity, and their implications in disease development, thereby aiding in the discovery of novel therapeutic targets and strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 312271-03-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,2,7 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.Calculate Digit Verification of CAS Registry Number 312271-03:
(8*3)+(7*1)+(6*2)+(5*2)+(4*7)+(3*1)+(2*0)+(1*3)=87
87 % 10 = 7
So 312271-03-7 is a valid CAS Registry Number.
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M2I-1
