312287-27-7Relevant articles and documents
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase
Gattinoni, Sonia,Simone, Chiara De,Dallavalle, Sabrina,Fezza, Filomena,Nannei, Raffaella,Battista, Natalia,Minetti, Patrizia,Quattrociocchi, Gianandrea,Caprioli, Antonio,Borsini, Franco,Cabri, Walter,Penco, Sergio,Merlini, Lucio,MacCarrone, Mauro
supporting information; experimental part, p. 4406 - 4411 (2010/10/02)
A series of oxime carbamates have been identified as potent inhibitors of fatty acid amide hydrolase (FAAH), an important regulatory enzyme of the endocannabinoid signaling system. Kinetic analysis indicates that they behave as non-competitive, reversible
