312329-89-8

Upstream product

• 558-13-4 carbon tetrabromide 
• 312329-75-2 N-allyl-N-formyl-4-methyl-benzenesulfonamide 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 

Downstream Products

• 312329-80-9 N-prop-2-en-1-yl-N-(2,2-dichlorovinyl)-4-methylbenzenesulfonamide 
• 312329-85-4 N-ethynyl-4-methyl-N-2-propan-1-yl-benzenesulfonamide 
• 312329-75-2 N-allyl-N-formyl-4-methyl-benzenesulfonamide 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 

Relevant academic research and scientific papers

Synthesis of ynamides from formamides

N-Formyl-tosylamides can be efficiently converted to N-ethynyl-tosylamides in two steps via the corresponding dichlorovinylamides.

Cs2CO3-Mediated Vicinal Thiosulfonylation of 1,1-Dibromo-1-Alkenes with Thiosulfonates: An Expedient Synthesis of (E)-1,2-Thiosulfonylethenes

A new and highly efficient vicinal thiosulfonylation of 1,1-dibromo-1-alkenes with thiosulfonates in the presence of cesium carbonate has been developed. The metal-free diheterofunctionalization is an operationally simple to access a wide range of (E)-1,2-thiosulfonylethenes (α-aryl-β-thioarylvinyl sulfones) in moderate to high yields with high levels of stereoselectivities. Further, scalable reactions have been demonstrated for this transformation, thus illustrating its efficiency and practicality. (Figure presented.).

Synthesis of ynamides and ynol ethers via formamides and formates

The efficient conversion of N-formyl-tosylamides to N-ethynyl-tosylamides via the corresponding dichlorovinylamides is described. Furthermore syntheses of N-formyl-tosylamides are reported.