312487-33-5

Upstream product

• 312487-37-9 (4R,6S)-4-[(R)-1-(tert-Butyl-diphenyl-silanyloxy)-propyl]-6-methyl-octanoic acid methyl ester 
• 312487-36-8 (E)-(4S,6S)-4-[(R)-1-(tert-Butyl-diphenyl-silanyloxy)-propyl]-6-methyl-oct-2-enoic acid methyl ester 
• 312487-31-3 (4R,6S)-4-[(R)-1-(tert-Butyl-diphenyl-silanyloxy)-propyl]-6-methyl-octan-1-ol 
• 312487-30-2 (E)-(4S,6S)-4-((R)-1-Hydroxy-propyl)-6-methyl-oct-2-enoic acid methyl ester 
• 312487-29-9 (Z)-3-[(2R,3R)-3-Ethyl-2-((S)-2-methyl-butyl)-oxiranyl]-acrylic acid methyl ester 
• 312487-26-6 (S)-4-Methyl-2-prop-(E)-ylidene-hexanoic acid methyl ester 
• 312487-28-8 [(2R,3R)-3-Ethyl-2-((S)-2-methyl-butyl)-oxiranyl]-methanol 
• 312487-27-7 (S)-4-Methyl-2-prop-(E)-ylidene-hexan-1-ol 
• 312487-32-4 (E)-(6R,8S)-6-[(R)-1-(tert-Butyl-diphenyl-silanyloxy)-propyl]-2,8-dimethyl-dec-2-enoic acid methyl ester 

Downstream Products

• 312487-35-7 (2S,6R,8S)-6-[(R)-1-(tert-Butyl-diphenyl-silanyloxy)-propyl]-2-hydroxy-2,8-dimethyl-3-oxo-decanoic acid methyl ester 

Relevant academic research and scientific papers

Synthetic study of polyoxypeptin: Stereoselective synthesis of the acyl side-chain segment

The first synthesis of the acyl side-chain segment of polyoxypeptin, a potent inducer of apoptosis in human pancreatic carcinoma AsPC-1, was accomplished. The key feature of the present synthesis is the stereospecific palladium-catalyzed hydrogenolysis of