312613-75-5Relevant academic research and scientific papers
Synthesis of alpha-substituted beta-amino acids using pseudoephedrine as a chiral auxiliary.
Nagula,Huber,Lum,Goodman
, p. 3527 - 3529 (2007/10/03)
[reaction: see text] beta-Amino acids are becoming increasingly attractive as intermediates in the synthesis of a variety of molecular structures. However, few methods are available for the synthesis of alpha-substituted beta-amino acids that are both readily scalable and highly stereoselective. Herein we report a new method for synthesizing alpha-substituted beta-amino acids that satisfies both of these requirements using enantiomerically pure pseudoephedrine as a chiral auxiliary.
